- What is 3X4? +
- Why 3X4 Genetics? +
- Technology +
- Ordering process +
- Practitioner portal +
- FAQs +
- Downloads +
The #1 genetic testing partner for visionary practitioners
Genetics is the best way to truly understand your patients and provide them with personalised health recommendations
3X4 is a genetic lifestyle test that evaluates over 157 individual SNPs that influence six key health areas: weight balance, heart health, blood sugar regulation, brain health, fitness and tissue health, and hormone health. The report provides tips and suggestions on diet, lifestyle, and supplements, based on the areas that are most at risk.
3X4 offers a turnkey solution to bring the power of a genetic lifestyle test into your practice so you can provide your patients with more personalised and actionable insights that will help them live better, longer, and healthier lives.
The 3X4 Test is not meant as a diagnostic tool, but is rather used as a preventative and screening tool to detect the root causes for the development of chronic conditions, and can be used to implement more targeted treatment.
The test can be used by anyone;
there are no limitations!
There is no age limit as your genes do not change, only your environment does. It could be used by someone who is interested in doing a deeper dive into their genetics, identifying their predispositions to chronic conditions, or someone who is eager to live a healthier lifestyle.
The science behind 3X4 is based on extensive research, combined with clinical practice to ensure that every recommendation we make is both scientifically accurate and proven to work in clinical practice.
Our scientific approach is based on three key principles

Systems approach
Our bodies are complex. 3X4 looks at how our genes work together in cellular pathways and functional systems to control processes such as inflammation, metabolism, and detoxification.

Going upstream
Traditionally, we have spent far too much time focusing on trying to fix symptoms. 3X4 wants to change this by understanding what is happening at a deeper cellular level so we can prevent, delay, or reverse disease.

Sustainable change
We believe that health is not a static condition, but a daily choice. Using the report and the guidance of an expert practitioner, you can gain a deeper understanding of your body and the daily choices you need to make.
Create a free account to join the 3X4 community.
Once logged in, you will notice a purple button at the top right-hand corner of the page that says, "Order a Test.". Click on it.
If your profile is set to 'Practitioner Pay', the payment link will be sent to your email address. If your profile is set to 'Patient Pay', the payment link will be sent directly to your patient.
Once ordered, you can check the status of an order at any time by viewing its status on the patients homepage, or by clicking on the hyperlinked order number for more details.
The go-to hub for efficiency, information, and support.
The 3X4 community and practitioner portal platforms seamlessly interlink, making life easier for our practitioners.

The 3X4 community
A place where like-minded healthcare practitioners can connect. A help and support network to navigate the ever-growing field of nutrigenomics.
Education, webinars, and live events, FREE mentorship sessions, marketing tools and support to take your practice to the next level, research resources, handy infographic tools, podcasts, and the list goes on!

The 3X4 portal
Order, track, and service your clients’ nutrigenomics needs through this portal. Interactive blueprint that highlights pathways and results for each report, making interpretation a breeze.
A comprehensive clinical guide that covers all aspects of the genes tested in the Blueprint Report. From SNPs to pathways, test pairing to recommendations, and even food sources and supplements, this guide is a vital resource for any nutrigenomics practice.
You can see all of the genes we test for in the sample report. Click here to download a sample report. Please contact us if you have not already received it! Data privacy is a top priority for us. We treat your patient’s personal information with the rigor and integrity it deserves, and our practices, procedures, policies, and technologies are designed to safeguard your patients’ privacy and health data. Rooted in science and clinical experienceOur industry-leading genetic lifestyle test is based on 20+ years of scientific research and clinical practice. Yael Joffe, PhD – 3X4’s founder and CSO – is acknowledged globally as an expert in the field of nutrigenomics and has been building clinically useful products for visionary practitioners for over two decades. The Scientific Advisory Board consists of top physicians, scientists, and experts in functional medicine who are closely involved in the advancement of our scientific thinking and help guide the creation of our tests and product development. A whole-body approach to healthInstead of looking at individual gene variants (known as SNPs) in isolation, the 3X4 Test uses a systems biology framework to more realistically analyse how genes work together in the body to impact overall health. Reports focused on ease and efficiencyThe 3X4 Blueprint Report uses infographics, explanations, and highly-actionable recommendations to give both the practitioner and patient a more meaningful understanding of their genetic baseline. Our recommendations are prioritised into the top three nutrition-related suggestions, supplements, and lifestyle changes per the patient’s three most genetically impactful pathways. The report is designed to make it simple to know where to start and how to prioritise meaningful lifestyle changes. A partner for practitioners3X4 Genetics gives practitioners the added value of an online community of like-minded visionary practitioners who collaborate, continually learn, and support one another as they lead their patients into the future of health. 3X4’s network of practitioners get exclusive access to educational workshops and events led by industry thought leaders, while enjoying the benefits of ongoing support from mentors and peers in the community. The 3X4 Blueprint Certification Course is a comprehensive 90-minute introduction to the new world of nutrigenomics, and how to bring it into your practice! We have condensed the essential facts, insights, and skills you will need into five efficient modules that combine theory with real-life case studies. You will graduate feeling confident and ready to conduct thorough and personalised 3X4 blueprint consultations in your practice. Click here to create your account and get started! |
Create an account for your own practitioner portal. It is free and only takes a minute. Log in and order your first patient test, which will be sent directly to your patient. Complete our online Blueprint Certification Course while you wait for the results. Our nutrigenomics education course takes only 90 minutes to complete and is entirely self-paced for your convenience. Yes! We have a special discounted kit price available to any practitioner who joins the 3X4 network. You can order your test via your practitioner portal once you have created your account. You will get your test kit, your blueprint report, and a 1-hour personalised consultation with one of our expert mentor practitioners. We highly encourage practitioners to join and ask questions on our 3X4 community page. You do not need to be a 3X4 practitioner to join, so feel free to send this link out to your colleagues. Yes! Feel free to offer the 3X4 Test on your website through any existing e-commerce system you have set up. However, you will need to place an order on your 3X4 practitioner portal once a patient requests a test via your website. The 3X4 Blueprint Certification Course is a comprehensive 90-minute introduction to the exciting new world of nutrigenomics, and how to bring it into your practice! We have condensed the essential facts, insights, and skills you will need into five efficient modules that combine theory with real-life case studies. You will graduate feeling confident and ready to conduct thorough and personalised 3X4 blueprint consultations in your practice. At this time, we only provide our test through licensed healthcare practitioners based in South Africa. We look forward to providing our service in more countries very soon. |
Next Biosciences
Ariane Avenue
International Business Gateway
Cnr. New Road and 6th Road
Midrand, South Africa