Genetics make up the baseline ‘code’ by which your body functions. Your genetic makeup influences the impact every single choice you make throughout your life. 3X4 tests over 157 genes that can affect your metabolism, inflammation, detoxication, fitness, weight, hormones, cognition, and response to your diet and supplements. By understanding how your unique genetics impact these key processes, you can make more intelligent, personalised, health decisions. There may even be insights you never imagined (like whether that second cup of coffee is a clever idea).

Our genetic lifestyle test is designed to provide clear insights and recommendations about areas of that are most important to you.

• Nutrient needs

  What are your body’s unique needs, and how do you respond to certain foods? How well do you tolerate fat and carbs? How much vitamin D do you need? Do you require extra antioxidants and omega-3 fats compared to others? Should you limit gluten, salt, or caffeine?

• Fitness strengths

  What type of exercise will your body respond to best? How can you train smarter in alignment with your genes for better performance, faster recovery, and fewer injuries?

• Proactive prevention

  Is your body more prone to high blood pressure, blood sugar, or cholesterol? How can you support your cardiovascular and immune system for more resilience as you age? 3X4 also looks at processes like inflammation, detoxication, methylation, and more.

• Ideal weight

  Why does your body resist weight loss, and how can you manage your weight in a healthy way?

• Stress strategies

  How does your life stress affect your brain health, hormones, sleep quality, and overall wellness? More importantly, what can you do about it?

Click to download a 3X4 sample report

Rooted in science

Our tests are based on 20+ years of scientific research and clinical practice. Yael Joffe (PhD), who leads the science team at 3X4, is acknowledged globally as an expert in the field of nutrigenomics. The Scientific Advisory Board of top physicians, scientists, and experts in functional medicine is integrally involved in the advancement of the scientific thinking.

Practitioner-guided

Genetics is complex. You should not be left alone to understand your genes. Our highly-trained practitioner partners will work with you to translate your results and analyse how your genes work together to impact your overall health.

Actionable insights in order of importance

The 3X4 Blueprint Report uses info graphics, explanations, and actionable recommendations that are prioritised into the top three suggestions for nutrition, supplements, and lifestyle changes for each of your most genetically impactful pathways (hence the name 3X4). This makes it easier to know where to start, and how to prioritise meaningful lifestyle changes.

Every gene has been selected based on scientific validity and actionability. The genes in the 3X4 Test were selected from peer-reviewed scientific publications. To ascertain scientific validity, we ensure adequate research to understand what the gene does, and how the version of the gene you possess affects your body. Every gene in your report has been handpicked because there is a documented action that your healthcare practitioner can recommend to reduce your risk and improve your health.

After sending in your genetic sample, results take 3-4 weeks to process. Your practitioner will contact you when your 3X4 report is available.

Our partner lab securely retains your sample until we are sure we have complete and accurate results to produce a report. The sample is destroyed 90 days after we have received your results.

Data privacy is a top priority for us. We treat your personal information with the rigour and integrity it deserves, and our practices, procedures, policies, and technologies are designed to safeguard your privacy and health data.

All information and connections are encrypted using SSL, an encryption-based internet security protocol, and we follow best practices that align with Health Insurance Portability and Accountability Act (HIPAA) and Protection of Personal Information (POPI) standards. For more details, check out How 3X4 Protects Genetic Data and read our Privacy Policy.

Our test kit is a simple, pain-free cheek swab that you can complete at home. A thorough rub with a cotton swab on the inside of each cheek for 60 seconds is all it takes. No spitting or blood draw is required.

Genetics and nutrigenomics, the study of how genes affect our diet and lifestyle choices, is still an emerging science, and proper interpretation of results requires specialised training. The 3X4 Test is only available through licensed and trained healthcare practitioners to ensure you get the most value from your genetic lifestyle test. All 3X4 practitioners are required to complete the 3X4 Blueprint Certification Course. They will evaluate your medical history, lifestyle, personal preferences, and environment in conjunction with your genetic information to create a personalised health intervention designed exclusively for you.

iPhone -

Open the camera and hold it over the QR code. A link will then appear. Tap on this link to go to the 3X4 homepage.

Android -

Google Lens and other camera apps have a QR code scanner.

Alternatively, manually type out the kit registration link, which is provided in the kit insert.