POCScreen is suitable for couples who have suffered a pregnancy loss, especially those who have had recurrent miscarriages.

Although many chromosomal abnormalities that cause miscarriages are sporadic and have a low recurrence risk, some abnormalities (such as translocations) are expected to significantly increase the risk of recurrence- which may necessitate parental karyotyping.

By identifying the (approximately) 50% of women whose pregnancy loss was due to chromosomal abnormalities, comprehensive chromosome screening will prevent a large proportion of patients undertaking unnecessary and costly evaluations. Furthermore, the psychological benefit of identifying the aetiology of a fetal loss, cannot be understated.

If a fetal chromosomal abnormality is excluded, there may be a possible treatable cause for a given miscarriage, and investigations can be focussed on identifying this.

Genetic testing outcomes can, therefore, be used to guide counselling for future pregnancies.

Next Biosciences uses next generation sequencing to rapidly and accurately screen Products of Conception (POC) for chromosomal abnormalities.

• >99% analytical specificity³
• >99% diagnostic accuracy³
• >99% analytical sensitivity³
• Test failure rate of 0.1% ²