Clinical Trials with Cord Blood Stem Cells

Table 1. Stem Cell Clinical Trials where children use their own (autologous) Cord Blood Stem Cells

Diagnosis Occurrence in USA Trial stage Trial registry
Acquired Hearing Loss 12.5% ages 6-19 phase 1 NCT01343394
NCT02038972
Autism 1.5% (1 in 68) children phase 2
phase 1
NCT01638819
NCT02176317
India
Cerebral Palsy 0.2% full term births,
2.2% premature births,
1 in 300 kids ages 5-10
phase 2 NCT01147653
NCT01072370
NCT01988584
Japan
Cerebral Palsy (see above) phase 1 Romania
Slovakia
Spain
Hypoplastic Left Heart Syndrome 0.2 per 1000 births phase 1 NCT01445041
NCT01856049
Neonatal Oxygen Deprivation 0.2% full term births phase 1 NCT00593242
NCT01506258
NCT01649648
Japan
Stroke (pre-/peri-natal) 1 per 3500 births phase 1 NCT02460484
Traumatic Brain Injury 435,000 per yr ages 0-14
#1 cause of death in kids
phase 1 NCT01251003
NCT01700166
Type 1 Diabetes 1.7 per 1000 ages birth-19 phase 1 & 2 NCT00989547
NCT00873925
CoRD

Table copyright Frances Verter, PhD 2014


Table 2. Stem Cell Clinical Trials using donor (allogeneic, includes siblings) Cord Blood Stem Cells

Diagnosis Occurrence in USA Trial stage Trial registry
Cartilage Repair 10-25% adolescents
have knee injuries
Approved by
Korean FDA
(Cartistem)
NCT01733186
Cerebral Palsy 2 per 1000 full term births phase 2 NCT01193660
NCT01528436
NCT01639404
NCT01991145
NCT02025972
Critical Limb Ischemia 2.5 per 1000 people,
over 80% of them diabetics
phase 1 NCT01019681
Premature Lungs (BPD) 25% births under 1500gm phase 2 NCT01897987
Type 1 Diabetes 1.7 per 1000 ages birth-19 phase 2 NCT01350219
NCT01996228

Table copyright Frances Verter, PhD 2014